Researchers created a technology capable of converting colon cancer cells into a state resembling normal cells

 

Researchers created a technology capable of converting colon cancer cells into a state resembling normal cells — avoiding the need to kill cancer cells and sidestepping harmful side effects.

 

The development was created by researchers at the Korea Advanced Institute of Science and Technology (KAIST) and was led by Professor Kwang-Hyun Cho.

 

This innovative approach is a departure from traditional treatments that destroy cancer cells but risk severe side effects and recurrence due to resistant cells. By creating a "digital twin" of the gene network that governs cell differentiation, the researchers identified key molecular switches that could revert cancer cells to their original, healthy state. 

 

Their findings were validated through cellular and animal studies, marking a significant step toward reversible cancer therapy.

 

"This research demonstrates the potential to systematically induce cancer cell reversion," said Professor Cho. "It introduces a novel concept of therapy that could minimize side effects and offer a new avenue for tackling various cancers."

 

The technology, supported by the Korean government, has been transferred to BioRevert Inc. to advance practical applications. If successful, this could pave the way for safer, more effective cancer treatments worldwide.